Platycodin D | ≥99%(HPLC) | Selleck | Immunology
Platycodin D. For research use only. Platycodin D, the main saponin isolated from Chinese herb Platycodonis Radix, exhibits anti-inflammatory, anti-allergic, cholesterol-lowering and neuroprotective properties. Next day delivery by 10:00 a.m. Order now.
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Platycodin D induces apoptosis and triggers ERK- and JNK
Platycodin D (PD) is one of the main saponins extracted from Platycodonis radix, and it possesses immune-stimulatory 2, anti-inflammatory 3,4, anti-nociceptive 5, anti-obesity 5,6, and anti
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Platycodon grandiflorus - An Ethnopharmacological
The triterpenoid saponin platycodin D is mainly isolated from the roots of Platycodon grandiflorum (Platycodi Radix or Jiegeng in Chinese), a plant with a long history of use as a traditional
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Establishment of indirect competitive enzyme linked
immunosorbent assay for the detection of platycodin D in Radix Platycodonis. Shuai Luo. 1, Yanfei He. 1, Hongxiang Sun* College of Animal Sciences, Zhejiang University, Hangzhou, Zhejiang, 310058, China. Abstract Platycodin D (PD) has been used as the quality control marker of Radix Platycodonis for its high content and various pharmacological
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Determination of Platycodin D and Platycodin D3 in Rat Plasma
PD-3% (Platycodon grandiflorum extracts powder including 3% of platycodin D), platycodin D, platycodin D3, platycodin A, platycodin D2, platyconic acid A, and platycoside E standards were donated by B&C Biopharm (Suwon, Republic of Korea). Notoginsenoside R1 (internal standard) was purchased from Fleton Natural Products Co., Ltd. (St. Huaishu
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Bioactive platycodins from Platycodonis Radix: Phytochemistry
Aside from the platycodins enriched extracts of Platycodonis Radix, purified platycodins including platycodin A, C, D and deapioplatycodin D showed inhibitory effect against the enzymatic activity of pancreatic lipase at the concentration of 500 μg/mL, which served as a potential mechanism of their anti-obesity activity (Xu, Han, Zheng, Lee
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Investigation of the Inhibitory Effect of Platycodin D in
Platycodin D is an active component isolated from Chinese herb Platycodonis radix with various pharmacological activities, such as antitussive, expectorant, anti-inflammatory, and analgesic effects.
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Platycodin D potentiates proliferation inhibition
Tang, Z. H. et al. Platycodin D from Platycodonis Radix enhances the anti-proliferative effects of doxorubicin on breast cancer MCF-7 and MDA-MB-231 cells. Chin Med-Uk. 9 (2014).
Get PriceAnalysis on herbal medicines utilized for treatment of COVID-19
Glycyrrhizae Radix et Rhizome, Scutellariae Radix, and Armeniacae Semen Amarum are the most frequently utilized in clinics, most of which are antipyretic (47, 26.26%), expectorant and cough-suppressing (22, 12.29%), and dampness-resolving (21, 11.73%) from traditional descriptions.
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platycodon grandiflorum root extract
PubMed: Platycodin D and D3 isolated from the root of Platycodon grandiflorum modulate the production of nitric oxide and secretion of TNF-alpha in activated RAW 264.7 cells. PubMed: Protective effect of saponins derived from roots of Platycodon grandiflorum on tert-butyl hydroperoxide-induced oxidative hepatotoxicity.
Get PriceRadix Platycodonis Extract - Platycodin manufacturers
professional Radix Platycodonis Extract - Platycodin supplier and manufacturer, Foodchem International Corporation has been supplying and exporting Radix Platycodonis Extract - Platycodin from China for almost 10 years, please be assured to buy Radix Platycodonis Extract - Platycodin at Foodchem.
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Platycodin D potentiates proliferation inhibition
Tang, Z. H. et al. Platycodin D from Platycodonis Radix enhances the anti-proliferative effects of doxorubicin on breast cancer MCF-7 and MDA-MB-231 cells. Chin Med-Uk. 9 (2014).
Get PriceA candidate gene identified in converting platycoside E to
Platycodin D and platycoside E are two triterpenoid saponins in Platycodon grandiflorus, differing only by two glycosyl groups structurally. Studies have shown β-Glucosidase from bacteria can
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platycodin D, 58479-68-8
PubMed:Platycodin D from Platycodonis Radix enhances the anti-proliferative effects of doxorubicin on breast cancer MCF-7 and MDA-MB-231 cells. PubMed: Platycodon grandiflorum root-derived saponins attenuate atopic dermatitis-like skin lesions via suppression of NF-κB and STAT1 and activation of Nrf2/ARE-mediated heme oxygenase-1.
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Neuroprotective activity of triterpenoid saponins from
Furthermore, to investigate and compare the neuroprotective activities of these triterpene saponins isolated from the total saponin fraction of P. radix, the activities of platycodin A, C, D and deapioplatycodin D were evaluated in glutamate-injured primary cultured rat cortical cells at concentrations ranging from 0.1 to 10 μM (Table 1). It
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platycodin D, 58479-68-8
PubMed:Platycodin D from Platycodonis Radix enhances the anti-proliferative effects of doxorubicin on breast cancer MCF-7 and MDA-MB-231 cells. PubMed: Platycodon grandiflorum root-derived saponins attenuate atopic dermatitis-like skin lesions via suppression of NF-κB and STAT1 and activation of Nrf2/ARE-mediated heme oxygenase-1.
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Platycodin D induces apoptosis and triggers ERK- and JNK
Platycodin D, the main saponin isolated from Chinese herb Platycodonis Radix, exhibits anticancer activities against various cancer cell lines. Here we evaluated its anticancer action against human hepatocellular carcinoma cells in vitro and in vivo, and elucidated the relationship between platycodin D-induced apoptosis and autophagy.
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Platycodon Grandiflorus | Encyclopedia
Wang, C.; Levis, G.B.S.; Lee, E.B. Platycodin D and D3 isolated from the root of platycodon grandiflorum modulate the production of nitric oxide and secretion of TNF-ɑin activated RAW 264.7 cells. Int. Immunopharm. 2004, 4, 0–1049. Yul Ly Hwang; Hyung Jin Ahn; Geun Eog Ji; Fermentation of Platycodi radix and bioconversion of platycosides
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Terpenoids’ anti-cancer effects: focus on autophagy
Platycodin D, isolated from the Chinese medicinal herb Platycodonis Radix, is a triterpenoid saponin with an eclectic variety of activities, namely anti-inflammatory [248, 249], anti-nociceptive , anti-obesity [251, 252], anti-atherogenic , immune-stimulatory , and neuroprotective . In addition, it exhibits antitumor activity on diverse cancer
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Science.gov
Previously, we identified a novel hypoglycemic action of a crude extract from Paeoniae Rubra Radix, which also suppressed phosphoenolpyruvate carboxykinase (PEPCK) gene transcription. Therefore, the current investigation intended to elucidate potential active bio-constituents of this herb and mechanisms of action.
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